Association of TAP and HLA class I antigen expression with tumor grade and disease stage grouped as low and advanced
| HLA class I antigens | TAP | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| + | − | Odds ratio* | + | − | Odds ratio | |||||||
| Grade | ||||||||||||
| Low (G1-G2) | 19 | 8 | 23 | 4 | ||||||||
| Adv. (G3) | 13 | 11 | 1.8 NS (P < 0.1) | 18 | 6 | 1.7 NS (P < 0.1) | ||||||
| Stage | ||||||||||||
| Low (I-II) | 24 | 6 | 27 | 3 | ||||||||
| Adv. (III) | 7 | 13 | 7.6† (P = 0.007) | 13 | 7 | 5.1† (P = 0.07) | ||||||
↵* Odds ratio of G3 or stage III lesions for negative versus positive TAP and HLA class I antigen phenotypes was calculated by logistic regression analysis with both TAP and HLA class I antigen phenotypes included in the models as independent variables. P corresponds to the likelihood ratio test on each variable.
↵† Interaction between TAP and HLA class I antigen phenotypes was not statistically significant (P > 0.1).