Table 1.

Relationship between APE1 and XRCC1 protein expression and tumor stage, grade, and response at first-check cystoscopy

FactorsMedian protein expression for APE1 as % (confidence interval, 25-75%)Mann-Whitney U (P)Median protein expression for XRCC1 as % (confidence interval, 25-75%)Mann-Whitney U (P)
Stage
    T298.7 (97.6-99.5)0.7597.4 (94.3-99.1)0.008
    T3/T498.8 (96.7-99.8)93.2 (94.9-97.8)
Grade
    298.5 (96.7-99.8)0.9796.3 (69.0-97.5)0.72
    398.7 (97.3-99.6)96.7 (80.5-98.9)
Response at first-check cystoscopy
    CR/PR98.7 (98.0-99.7)0.1396.7 (82.7-98.9)0.20
    PD/RP98.0 (92.3-99.2)91.7 (56.0-98.0)
  • NOTE: Rapid progression describes those patients where cystoscopy was not done (n = 11, see text for details).

    Abbreviations: CR/PR, complete response/partial response; PD/RP, progressive disease/rapid progression.