Table 3.

Frequencies of H. pylori infection in controls and noncardia gastric cancer cases of different IL-8 −251 genotypes

GenotypesTotalH. pylori positive (%)ControlsH. pylori positive in controls (%)Gastric cancer casesH. pylori positive in gastric cancer cases (%)
AA10052 (52.0)5625 (44.6)4427 (61.4)
AT291160 (55.0)12754 (42.5)164106 (64.6)
TT264145 (54.9)10847 (43.5)15698 (62.8)
Total655357 (54.5)291126 (43.3)364231 (63.5)
  • NOTE: H. pylori infection was assessed by CLO urease test, Giemsa staining of biopsy specimens, or 13C-urea breath test. Comparison of H. pylori infection between noncardia gastric cancer cases and controls was analyzed by χ2 test (OR, 2.27; 95% CI, 1.66-3.12; χ2 = 26.51; P < 0.0001). IL-8 −251 genotypes versus H. pylori infection: total subjects χ2 = 0.089; P = 0.956; controls: χ2 = 0.029; P = 0.985; gastric cancer cases: χ2 = 0.047; P = 0.977.