Table 6.

Stratification analysis of IL-8 −251A/T genotypes, ORs, and 95% CIs by selected variables

VariableControl subjects (n = 308)
Gastric cancer case subjects (n = 470)
OR (95% CI)
AA, n (%)ATTTAT + TTAA, n (%)ATTTAT + TTAATTAT + TT
All*62 (20.1)138 (44.8)108 (35.1)246 (79.9)59 (12.6)213 (45.3)198 (42.1)411 (87.4)1.001.93 (1.26-2.95)1.76 (1.19-2.59)
Age (y)
    <506 (18.7)15 (46.9)11 (34.4)26 (81.3)7 (11.8)26 (51)18 (37.2)44 (88.2)1.001.40 (0.37-5.27)1.45 (0.44-4.78)
    50-6526 (21.1)52 (42.3)45 (36.6)97 (78.9)24 (12.7)82 (43.4)83 (43.9)165 (87.3)1.002.00 (1.03-3.88)1.84 (1.00-3.39)
    >6530 (19.6)71 (46.4)52 (34.0)123 (80.4)28 (12.2)105 (45.7)97 (42.1)202 (87.8)1.002.00 (1.08-3.70)1.76 (1.00-3.09)
Sex
    Female27 (21.4)51 (40.5)48 (38.1)99 (78.6)27 (12.8)96 (45.7)87 (41.5)183 (87.2)1.001.81 (0.96-3.44)1.85 (1.03-3.32)
    Male35 (19.2)87 (47.8)60 (33.0)147 (80.8)32 (12.3)117 (45.0)111 (42.7)228 (87.7)1.002.02 (1.14-3.59)1.70 (1.01-2.86)
Ethnicity§
    Ethnic A23 (19.5)54 (45.8)41 (34.7)95 (80.5)34 (11.9)131 (45.6)122 (42.5)253 (88.1)1.002.01 (1.07-3.80)1.80 (1.01-3.22)
    Ethnic B38 (20.5)83 (44.9)64 (34.6)147 (79.5)21 (12.0)82 (46.9)71 (41.1)153 (88.0)1.002.04 (1.08-3.82)1.88 (1.06-3.36)
        Hoklo29 (20.0)66 (45.5)50 (34.5)116 (80.0)15 (12.1)58 (46.8)51 (41.1)109 (87.9)1.001.97 (0.55-4.11)1.82 (0.92-3.57)
        Hakka9 (22.5)17 (42.5)14 (35.0)31 (77.5)6 (12.0)24 (48.0)20 (40.0)44 (88.0)1.002.14 (0.62-7.39)2.13 (0.69-6.60)
  • * Cases included cardia and noncardia gastric carcinomas.

  • χ2 test, P < 0.05.

  • χ2 test, P > 0.05.

  • § Five control subjects and nine gastric carcinoma patients were not counted because of uncertain ethnicity; ethnic B = Hoklo + Hakka.