Table 2.

Associations between membranous CD24 expression and clinicopathologic variables

CharacteristicmCD24 negativemCD24 weakmCD24 moderatemCD24 strongP
All cases
46 (31.3%)33 (22.4%)43 (29.3%)25 (17%)
Age
    ≤65 y26 (36.1%)16 (22.2%)17 (23.6%)13 (18.1%)0.342*
    >65 y20 (26.7%)17 (22.7%)26 (34.6%)12 (16%)
Dukes stage
    A9 (27.3%)9 (27.3%)9 (27.3%)6 (18.1%)0.412
    B18 (33.3%)15 (27.8%)13 (24.1%)8 (14.8%)
    C17 (35.4%)9 (18.8%)17 (35.4%)5 (10.4%)
    D2 (16.7%)0 (0%)4 (33.3%)6 (50%)
Tumor stage
    pT12 (22.2%)1 (11.1%)4 (44.5%)2 (22.2%)0.677
    pT211 (32.4%)9 (26.5%)9 (26.5%)5 (14.6%)
    pT329 (30.9%)21 (22.3%)27 (28.7%)17 (18.1%)
    pT44 (40%)2 (20%)3 (30%)1 (10%)
Nodal status
    pN027 (30.7%)24 (27.3%)24 (27.3%)13 (14.7%)0.400
    pN110 (34.5%)4 (13.8%)10 (34.5%)5 (17.2%)
    pN29 (30%)5 (16.7%)9 (30%)7 (23.3%)
Distant metastasis
    Mx44 (32.6%)33 (24.4%)39 (28.9%)19 (14.1%)0.006*
    pM12 (16.7%)0 (0%)4 (33.3%)6 (50%)
Grade
    11 (16.7%)2 (33.3%)0 (0%)3 (50%)0.317
    239 (33.3%)28 (23.9%)35 (29.9%)15 (12.9%)
    36 (25%)3 (12.5%)8 (33.3%)7 (29.2%)
Localization
    Left colon24 (40%)14 (23.3%)12 (20%)10 (16.7%)0.013
    Transversal colon5 (23.8%)3 (14.3%)13 (61.9%)0 (0%)
    Right colon10 (22.7%)13 (29.6%)10 (22.7%)11 (25%)
    Rectum7 (31.8%)3 (13.6%)8 (36.4%)4 (18.2%)
  • Abbreviation: mCD24, membranous CD24 expression.

  • * Fisher's exact test.

  • χ2 test for trends.

  • χ2 test.