Table 4.

Comparison of HER-2 status determined by FISH and by 10H8-IHC in the BCIRG central laboratories

10H8-IHC scores (0-3+)
01+2+3+Total
FISH negative (%)1,281 (94.6)329 (85.5)46 (19.4)3 (1.1)1,659 (74.0)
FISH positive (%)73 (5.4)56 (14.5)191 (80.6)264 (98.9)584 (26.0)
Total (%)1,354 (100)385 (100)237 (100)267 (100)2,243 (100)