Table 2.

List of 15 down-regulated genes after transfection of siRNA against S100A6

Fold changePGene bank IDGene name (symbol)Putative cellular function
0.0700.0288NM_014624.2S100 calcium-binding protein A6 (S100A6)Proliferation, invasion
0.3430.0229D38553.1HCAP-HMitotic regulation
0.3620.0057M29550.1Calcineurin A1Antiapoptotic effect
0.3820.0147AB077208.1Thymidylate synthaseMetabolism (related to drug sensitivity)
0.3820.0006NM_003651.1Cold shock domain protein ARepressor of transcription
0.3870.0086AJ278112.1DEP domain containing 1Cell cycle control
0.3910.0007BG391171Thymopoietin (TMPO)Proliferation
0.3920.0118AV725328Prion proteinAntiapoptotic effect
0.3970.0230NM_018492.1T-cell originated protein kinase (TOPK)Related to MAPK
0.3990.0252AU153848GTPase-activating proteinSignal transduction
0.4140.0309BE045993Opa-interacting protein 5Not characterized
0.4140.0267Z25425.1Never in mitosis gene a (NIMA)–related kinase 2 (NEK2)Mitotic regulation
0.4160.0002NM_003158.1Serine/threonine kinase 6 (STK6/Aurora-A/STK15)Mitotic regulation
0.4170.0345BC002703.1Centromere protein ARelated to mitotic behavior of chromosomes
0.4190.0081AF213040.1Mutant cyclin-dependent kinase-associated protein phosphataseCell cycle regulator
  • Abbreviation: MAPK, mitogen-activated protein kinase.