Table 3.

List of 15 up-regulated genes after transfection of siRNA against S100A6

Fold changePGene bank IDGene name (symbol)Putative cellular function
6.9860.0085AW003173 stanniocalcin 1Cell metabolism, cellular calcium/phosphate homeostasis.
4.6430.0164M13436.1Human ovarian β-A inhibinNegative regulator of cell proliferation, tumor suppressor activity
4.1150.0312NM_000450.1Selectin E precursor cellAdhesion molecules
3.9470.0361BC002827.1Tropomyosin 4Actin-binding proteins involved in the contractile system of the cytoskeleton of cells
3.4710.0078NM_005114.1Heparan sulfate d-glucosaminyl 3-O-sulfotransferase 1 precursorThe heparan sulfate biosynthetic enzyme family
3.1270.0056M57731.1Cytokine gro-βAntiproliferative effect
2.9810.0009NM_004591.1Small inducible cytokine subfamily A (Cys-Cys), member 20 (SCYA20)Antiproliferative or proliferative effect (cell type specific)
2.9340.0247AK023795.1Metalloproteinase with thrombospondin type 1 motifs ADAMTS1 (ADAMTS1)Antiangiogenic activity/inhibitor of endothelial cell proliferation
2.9280.0248AF043337.1Interleukin 8 COOH-terminal variant (IL8)Chemoattractant
2.9040.0216AF240698.1Retinol dehydrogenase homologue isoform-1 (RDH)Retinoid metabolism
2.8330.0091AF240697.1Retinol dehydrogenase homologue isoform-2 (RDH)Retinoid metabolism
2.5950.0191NM_001674.1Activating transcription factor 3 long isoformProapoptotic, antiproliferative, and anti-invasive effect
2.5850.0092NM_018936.1Protocadherin β2Cell-cell connections
2.5790.0337NM_005771.1Retinol dehydrogenase homologue (RDHL)Retinoid metabolism, colonocyte differentiation
2.5640.0092NM_006290.1TNFα-induced protein 3 (TNFAIP3)Inhibit NF-κB activation and TNF-mediated apoptosis
  • Abbreviations: NF-κB, nuclear factor-κB; TNF, tumor necrosis factor.