Table 1.

Baseline patient characteristics

CharacteristicValue
Baseline screening
    Total studied97
    Age (y)57 (24-81)
    Sex (male/female)40 (41)/57 (59)
    Body surface area (m2)1.78 (1.30-2.37)
Primary tumor site
    Bladder5 (5)
    Breast39 (40)
    Esophagus17 (17)
    Lung10 (10)
    Ovary18 (18)
    Miscellaneous8*
Pretherapy chemistry and hematology
    Alanine aminotransferase (units/L)20 (2.0-264)
    Alkaline phosphatase (units/L)121 (38-1030)
    Aspartate aminotransferase (units/L)21 (6.0-187)
    γ-Glutamyltransferase (units/L)35 (9.0-1567)
    Serum creatinine (μmol/L)72 (20-145)
    Total bilirubin (μmol/L)7.0 (3.0-24)
    Hematocrit (L/L)0.37 (0.20-0.45)
    WBC (× 109 per L)7.2 (2.9-32)
    Absolute neutrophil count (×109/L)4.7 (0.90-14)
  • NOTE: Continuous data are given as median with range in bracket, and categorical data as number of patients with percentage of the total population in parenthesis.

  • * Primary sites include adenocarcinoma of unknown primary site (3), head and neck (1), kidney (1), tongue (2), penis (1).