Table 3.

Summary of immunohistochemical staining for the EZH2 protein in bladder tissue specimens

Specimen pathologyNo. specimens% Nuclei expressing EZH2 protein
NontumorTumorP
Overall3969.1 ± 14.278.1 ± 9.3<0.005*
Superficial (Ta/Tis/T1)2769.4 ± 14.677.8 ± 8.3<0.005
Invasive (T2/T3)1268.5 ± 13.778.7 ± 9.7<0.005
Low grade672.4 ± 11.477.5 ± 8.30.41§
High grade3368.5 ± 14.878.2 ± 9.5<0.005
  • * Comparison of EZH2 expression in all tumors versus adjacent nontumor bladder specimens.

  • Comparison of EZH2 expression in superficial tumors versus adjacent nontumor bladder specimens.

  • Comparison of EZH2 expression in invasive tumors versus adjacent nontumor bladder specimens.

  • § Comparison of EZH2 expression in low-grade tumors versus adjacent nontumor bladder specimens.

  • Comparison of EZH2 expression in high-grade tumors versus adjacent nontumor bladder specimens.