Table 1.

Top 100 classifier probe sets predicting erlotinib sensitivity in NSCLC cell lines

Class: sensitive
Class: insensitive
S/N scorePUniGene IDCommon gene nameS/N scorePUniGene IDCommon gene name
1.525.9e−07Hs.348553Immortalization-up-regulated protein11.2e−03Hs.435800Vimentin
1.41.5e−05Hs.95549Hypothetical protein FLJ202730.979.5e−04Hs.250687TRP-1 protein
1.43.2e−06Hs.95549Hypothetical protein FLJ202730.931.0e−02Hs.232068Transcription factor 8 (TCF8)
1.371.0e−06Hs.439180Chromosome 19 open reading frame 210.922.1e−04Hs.508741Neuronal protein 3.1
1.32.9e−05Hs.278611Polypeptide N-acetylgalactosaminyltransferase 30.926.7e−04Hs.250687TRP-1 protein
1.33.0e−06Hs.339P2Y purinoceptor 20.927.9e−04Hypothetical protein LOC284267
1.263.7e−05Hs.95549Hypothetical protein FLJ202730.893.9e−05Hs.433394Tubulin α-3
1.242.8e−06Hs.415770Connexin 310.873.7e−04Hs.99865Epimorphin
1.241.8e−05Hs.148074Plakophilin 30.872.0e−05Hs.32374Deltex-3
1.241.4e−05Hs.380684Phosphatidate cytidylyltransferase 10.865.6e−03Hs.164467Transcriptional repressor AP-2rep
1.233.2e−05Hs.76550MAL2 protein0.851.7e−03Hs.416385Insulin-induced gene 1 protein
1.22.5e−05Hs.380684Phosphatidate cytidylyltransferase 10.847.6e−03Hs.22451FLJ10357 protein
1.191.0e−04Hs.23582Tumor-associated calcium signal transducer 20.846.9e−04Hs.437379Up-regulated in liver cancer 1
1.171.6e−04Hs.194657E-cadherin0.841.5e−02Hs.301711Hypothetical protein LOC387882
1.174.5e−05Hs.31439SPINT20.831.1e−03Hs.40368Sigma-adaptin 1B
1.165.0e−05Hs.254605Microtubule-associated protein 70.821.3e−02Hs.9999Hematopoietic neural membrane protein
1.132.1e−05Hs.55279Maspin0.813.4e−04Hs.508741Neuronal protein 3.1
1.112.9e−04Hs.184510Stratifin0.811.4e−03Hs.511758Centrosomal colon cancer autoantigen protein
1.091.1e−04Hs.380684Phosphatidate cytidylyltransferase 10.816.4e−04Hs.40368Sigma-adaptin 1B
1.081.1e−05Hs.148074Plakophilin 30.82.4e−04Hs.387856TPR repeat containing protein KIAA1043
1.081.1e−06Hs.11669Laminin α-5 chain0.81.7e−02Hs.354740Calcium-activated potassium channel αsubunit 1
1.086.6e−04Hs.184510Stratifin0.795.4e−04Hs.40368σ-Adaptin 1B
1.071.7e−05Hs.415770Connexin 310.782.1e−02Hs.130865Dickkopf-3
1.063.5e−04Hs.21420Serine/threonine-protein kinase PAK 60.771.1e−03Hs.250687TRP-1 protein
1.041.8e−04Hs.376874Potassium channel subfamily K member 10.772.2e−03Hs.380138N-chimaerin
1.041.1e−04Hs.440411Transcription factor AP-2γ0.771.5e−02Hs.232068Transcription factor 8 (TCF8)
1.033.9e−05Hs.193490Hypothetical protein FLJ319520.774.4e−03Hs.109672ST6GALNAC6
1.031.6e−04Hs.152423Hypothetical protein FLJ212740.771.2e−03Hs.306298ZNF682
1.022.4e−05Hs.193490Hypothetical protein FLJ319520.768.3e−03Hs.150406Zinc finger protein 37 homologue
1.015.2e−05Hs.165904Epsin-30.761.8e−02Hs.387385SMURF2
11.1e−04Hs.513684Unknown EST0.763.1e−03Hs.356109DKFZp762F237
0.992.3e−04Hs.51133BRK0.751.1e−02Hs.25220Glycosyltransferase-like protein LARGE
0.997.1e−05Hs.67776FLJ46072 protein0.755.5e−03Hs.438669Insulin receptor
0.993.4e−04Hs.396798β-1,4-galactosyltransferase 10.743.7e−04Hs.40368σ-Adaptin 1B
0.993.7e−05Hs.95549Hypothetical protein FLJ202730.744.3e−03Hs.29595PRA1 family protein 2
0.992.6e−04Hs.298079KLC2L protein0.744.6e−02Hs.270435Hypothetical protein FLJ12985
0.984.7e−04Hs.21420Serine/threonine-protein kinase PAK 60.746.7e−05Hs.285673Protein C14orf159
0.981.5e−03Hs.56937ST14 protein0.739.2e−02Hs.76118Ubiquitin carboxyl-terminal hydrolase isozyme L1
0.989.6e−05Hs.26765LOC58489 protein0.735.0e−05Hs.25132KIAA0470 protein
0.987.2e−04Hs.417795Dermokine-β0.739.3e−03Hs.232068Transcription factor 8 (TCF8)
0.974.4e−04Hs.194657E-cadherin0.721.1e−04Hs.512712Tubulin, β
0.971.7e−03Hs.233950HAI-10.723.0e−02Hs.164267Dual-specificity tyrosine-phosphorylation regulated kinase 3
0.977.2e−05Hs.377416Engulfment and cell motility protein 30.724.2e−02Hs.37196GPR protein
0.971.1e−03Hs.528844Unknown EST0.717.9e−04Hs.60177Zinc finger protein DZIP1
0.966.6e−04Hs.75746Aldehyde dehydrogenase 1A30.711.2e−02Hs.22451FLJ10357 protein
0.964.5e−04Hs.178695Mitogen activated protein kinase p38 δ0.79.9e−03Hs.148258Protein C16orf45
0.965.4e−04Hs.24743FLJ20171 protein0.74.2e−02Hs.50150Unknown EST
0.952.8e−05Hs.427719PARX protein0.71.5e−02Hs.370049Hypothetical protein FLJ26472
0.945.0e−04Claudin-70.697.8e−03Hs.412117Annexin A6
0.947.4e−04Hs.18894Adaptor-related protein complex 1, μ2 subunit0.697.5e−03Hs.298258Unknown EST