Characterisitics of 52 individuals at risk harboring preneoplastic lesions (preneoplastic lesions: squamous metaplasia, mild, moderate, and severe dysplasia) in the central airways at baseline bronchoscopic examinations
| Total number of individuals | 52 | |
|---|---|---|
| Gender: | ||
| Male | 44 | |
| Female | 8 | |
| Median age (y), (range) | 64 (42-78) | |
| COPD | 31 | |
| Non-COPD | 21 | |
| Smoking history | ||
| Current smokers | 12 | |
| Ex-smokers | 38 | |
| Never-smokers | 2 | |
| Median no. (range) of pack-years smoked | 39.5 (0-120) | |
| Age (range) at smoking initiation | 19 (8-27) | |
| Median no. years (range) after smoking cessation | 3.5 (1-39) | |
| Medical history | ||
| Group 1: at risk for lung cancer primary | 21 | |
| Group 2: at risk for subsequent primary | ||
| Past ENT cancer | 8 | |
| Past lung cancer treated surgically | 11 | |
| Past lung cancer treated bronchoscopically | 5 | |
| ≥2 primaries: ENT-Lung; Lung-Lung | 7 | |
| Total no. of bronchoscopies | 237 | |
| Median no. (range) of bronchoscopies per subject | 4 (2-19) | |
| Total no. of lesions (preneoplastic lesions) sampled longitudinally | 483 | |
| Median no. lesions (preneoplastic lesions) sampled per subject | 5 (2-61) | |