Table 2

The effects of cetuximab on cell cycle distribution in a panel of NSCLC cell lines exposed to 100 nmol/L for 24 hours

Cell lineMFI% G0/G1% S% G2-MP*
H292-Squamous21
    0 nmol/L C225353629
    100 nmol/L C225662014< 0.0001
H322-BAC16
    0 nmol/L433225
    100 nmol/L552421< 0.0001
H358-BAC5.7
    0 nmol/L315118
    100 nmol/L394417< 0.0001
A549-Ad14
    0 nmol/L C225493714
    100 nmol/L C225553510< 0.0001
Calu3-Adenocarcinoma8.9
    0 nmol/L50428
    100 nmol/L55378< 0.0001
H157-Squamous13
    0 nmol/L C225553015
    100 nmol/L C225552817N.S.
H520-Squamous0
    0 nmol/L C225414118
    100 nmol/L C225414217N.S.
  • Abbreviation: N.S., not significant.

  • * Per χ2 test.