Table 1

Characteristics of the 99 patients with diffuse large B-cell lymphoma by FOXP1 protein expression status

Characteristics/outcomeFOXP1-negative
FOXP1-positive
n (%)n (%)
Total59 (100)40 (100)
Gender
    Male30 (50)22 (55)
    Female29 (50)18 (45)
Age
    Median (y)5965
    Range (y)15-9235-86
Stage
    I17 (29)10 (25)
    II21 (36)7 (18)
    III5 (8)5 (12)
    IV16 (27)18 (45)
Symptoms
    A41 (69)22 (55)
    B18 (31)18 (45)
Performance status
    021 (35.5)10 (25)
    121 (35.5)10 (25)
    28 (14)8 (20)
    37 (12)9 (22)
    42 (3)3 (8)
    0-142 (71)20 (50)
    2-417 (29)20 (50)
Lactate dehydrogenase* (IU)
    ≤21034 (63)15 (44)
    210-42015 (28)8 (24)
    >4205 (9)11 (32)
IPI
    0-132 (54)12 (30)
    2-319 (32)16 (40)
    4-58 (14)12 (30)
Overall survival
    Median (y)12.21.6
    5 y (%)6939
Progression-free survival
    Median (y)5.71.25
    5 y (%)5739
  • * Upper limit of normal 210 IU; not available for 11 patients (5 FOXP1-negative and 6 FOXP1-positive).