Table 3

Relationship between Slug expression and clinicopathologic findings according to E-cadherin expression

E-cadherin; preserved
E-cadherin; reduced
Slug(+), n = 31 (35%)Slug(−), n = 57 (65%)PSlug(+), n = 67 (58%)Slug(−), n = 48 (42%)P
Histology
    Well17 (54.8)15 (26.3)0.02331 (46.3)12 (25.0)0.0298
    Moderate10 (32.3)34 (59.7)25 (37.3)20 (41.7)
    Poor4 (12.9)8 (14.0)11 (16.4)16 (33.3)
Tumor depth
    pT112 (38.7)39 (68.4)0.00096 (9.0)11 (22.9)NS
    pT22 (6.5)10 (17.5)14 (20.9)4 (8.3)
    pT310 (32.3)5 (8.8)33 (49.3)25 (52.1)
    pT47 (22.6)3 (5.3)14 (20.9)8 (16.7)
pN
    pN020 (64.5)43 (75.4)NS14 (20.9)16 (33.3)NS
    pN111 (35.5)14 (24.6)53 (79.1)32 (66.7)
pM
    pM026 (83.9)53 (93.0)NS34 (50.8)36 (75.0)0.0077
    pM15 (16.1)4 (7.0)33 (49.2)12 (25.0)
Stage
    I9 (29.0)33 (57.9)0.0232 (3.0)6 (12.5)0.041
    IIA9 (29.0)9 (15.8)9 (13.4)9 (18.8)
    IIB3 (9.7)9 (15.8)5 (7.5)7 (14.6)
    III5 (16.1)2 (3.5)18 (26.9)14 (29.1)
    IV5 (16.1)4 (7.0)33 (49.2)12 (25.0)
Lymphatic invasion
    Negative15 (48.4)35 (61.4)NS15 (22.4)19 (39.6)0.0472
    Positive16 (51.6)22 (38.6)52 (77.6)29 (60.4)
Venous invasion
    Negative19 (61.3)49 (86.0)0.009642 (62.7)33 (68.8)NS
    Positive12 (38.7)8 (14.0)25 (37.3)15 (31.2)