Table 2

Representative monoclonal antibodies used for targeted therapy for colorectal carcinoma

Antibody nameTargetReference
Cetuximab (Imclone/Bristol Myers Squibb)EGFR(11)
ABX-EGF (Abgenix/Amgen)EGFR(12)
EMD 72000 (Merck)EGFR(13)
Edrecolomab (Centocor/GlaxoSmithKline)Ep-CAM(14)
Bevacizumab (Genentech)VEGF(15)
  • Abbreviations: Ep-CAM, 17-1A antigen; VEGF, vascular endothelial growth factor.