Table 1

Impact of imatinib on cytokine and chemokine secretion of immature MDCs

+DMSO+Imatinib
1 μmol/L3 μmol/L5 μmol/L
Monocyte chemoattractant protein-1 (CCL2; pg/mL)
    Donor 1>2,000254.746.724.5
    Donor 21,862.0947.2278.2335.5
    Donor 31,637.51,584.7672.4403.3
Rantes (CCL5; pg/mL)
    Donor 1<0.1<0.1<0.1<0.1
    Donor 230.135.834.743.7
    Donor 332.538.265.272.8
Tumor necrosis factor-α (pg/mL)
    Donor 17.15.36.13.4
    Donor 219.214.713.49.9
    Donor 358.643.949.459.3
IL-6 (pg/mL)
    Donor 1<0.11.20.9<0.1
    Donor 212.612.916.117.1
    Donor 35.56.35.28.1