Table 3

Characteristics of tumors based on MSI or MMR status

MSI-H (%)MSS and MSI-L (%)PMMR-negative (%)MMR-positive (%)PTotal (%)
Female10 (38.5)115 (48.7)0.301511 (39.3)120 (51.3)0.3175131 (50.0)
Male16 (61.5)121 (51.3)17 (60.7)114 (48.7)131 (50.0)
Caucasian18 (69.2)162 (68.6)1.000020 (71.4)160 (68.4)0.8317180 (68.7)
African-American8 (30.8)74 (31.4)8 (28.6)74 (31.6)82 (31.3)
Proximal23 (88.5)113 (47.9)<0.000125 (89.3)111 (47.4)<0.0001136 (51.9)
Distal3 (11.5)123 (52.1)3 (10.7)123 (52.6)126 (48.1)
Grade
    I4 (15.4)32 (13.6)0.03374 (14.3)32 (13.7)0.066436 (13.7)
    II15 (57.7)181 (76.7)17 (60.7)179 (76.5)196 (74.8)
    III7 (26.9)23 (9.7)7 (25.0)23 (9.8)30 (11.5)
Tumor invasion
    T11 (3.8)13 (5.5)0.30851 (3.6)13 (5.6)0.204514 (5.3)
    T29 (34.6)44 (18.6)9 (32.1)44 (18.8)53 (20.2)
    T314 (53.8)151 (64.0)15 (53.6)150 (64.1)165 (63.0)
    T42 (7.7)28 (11.9)3 (10.7)27 (11.5)30 (11.5)
Clinical stage
    I7 (26.9)45 (19.1)0.61558 (28.6)44 (18.8)0.557352 (19.8)
    II9 (34.6)69 (29.2)9 (32.1)69 (29.5)78 (29.8)
    III4 (15.4)46 (19.5)4 (14.3)46 (19.7)50(19.7)
    IV6 (23.1)76 (32.2)7 (25.0)75 (32.1)82 (31.3)
    Mean age65.365.765.665.765.7