Table 1.

Association between TF expression and clinicopathologic variables

TF expression
Low TF (<25%, n = 63)
VariablesNegative TF (0%, n = 13)Weak TF (0%<, n = 50)High TF (≥25%, n = 50)P value (Low vs. High)
Age (y)
    <6582624
    ≥65524260.5284
Gender
    Male73134
    Female619160.3989
Extent of the primary tumor spread
    pT1331
    pT2395
    pT342015
    pT4318290.0043*
Lymph node metastasis
    pN0275
    pN1a102011
    pN1b123340.0043*
Distant metastasis
    pM094228
    pM148220.0041*
    M1 (LYM)27190.0039*
    M1 (HEP)1110.9999
    M1 (PER)1020.5508
Stage
    I141
    II022
    III5237
    IVA31318
    IVB48220.0002*
Histopathologic tumor grade
    G172416
    G252323
    G313110.0164*
Lymphatic invasion
    Negative458
    Positive945420.8001
Vascular invasion
    Negative81412
    Positive536380.2087
Perineural invasion
    Negative264
    Positive1144460.5443
Growth pattern
    Expansive + intermediate93021
    Infiltrative420290.0392*
Surgical margin
    Negative103430
    Positive316200.2744
  • * Significant.

  • LYM, lymphatic metastasis; HEP, hepatic metastasis; PER, peritoneal metastasis.

  • Classified according to the classification of Pancreatic Carcinoma of Japan Pancreas Society.