Table 2.

Prognostic factors in Cox's proportional hazards model

Univariate
Multivariate
VariablesHazard ratio95% Confidence intervalPHazard ratio95% Confidence intervalP
Age (y)
    ≥65/<651.2020.782-1.8460.4014
Gender
    Female/male0.9090.582-1.4200.6762
Extent of the primary tumor spread
    pT4/pT1-pT31.5451.001-2.3850.0497*1.2800.793-2.0660.3125
Lymph node metastasis
    pN1a, pN1b/pN02.7701.274-6.0230.0102*2.9531.292-6.7520.0103*
Distant metastasis
    pM1/pM02.3011.279-3.2230.0027*1.5010.912-2.4710.1101
Histologic tumor grade
    G2, G3/G11.8451.182-2.8790.0070*1.8821.128-3.3180.0154*
Lymphatic invasion
    Positive/negative1.4290.757-2.7000.2708
Vascular invasion
    Positive/negative1.4120.877-2.2730.1554
Tumor diameter (cm)
    ≥3.5/<3.51.3660.884-2.1110.1604
Growth pattern
    Infiltrative/expansive, intermediate1.6381.096-2.5840.0173*1.2110.742-1.9760.4446
Surgical margin
    Positive/negative1.1680.747-1.8240.4959
Chemoradiotherapy
    Not received/received0.9570.562-1.6300.8708
TF expression
    High TF/low TF2.7231.748-4.243<0.0001*2.0141.205-3.3660.0076*
  • * Significant.