Diameter of erythema at dendritic cell injection sites (mean ± SD)
| (A) Longest diameter of erythema at dendritic cell injection site after first injection and at the time point with maximum reactivity | ||||
|---|---|---|---|---|
| First | Maximum | |||
| CEA (mm) | 40 ±14 | 59 ± 25* | ||
| Tet | 34 ± 35 | 56 ± 41 | ||
| CMV | 7 ± 12 | 17 ± 18 | ||
| (B) Average change of diameter of erythema at dendritic cell injection site between first injection and maximum reactivity for patients with stable disease versus progressive disease | ||||
| Stable disease | Progressive disease | |||
| ΔCEA (mm) | 34 ± 24 | 7 ± 13† | ||
| ΔTet | 28 ± 31 | 19 ± 20 | ||
| ΔCMV | 12 ± 13 | 10 ± 15 | ||
NOTE: Δ refers to the difference between the diameter at the first injection site and the time of maximum DTH response.
↵* P < 0.05 for comparison of diameter of response at dendritic cells + rF-CEA(6D)-TRICOM injection site for the first injection and at the maximal response using Student's t test.
↵† P < 0.05 for the comparison of patients with stable disease/minor response and those with progressive disease using Student's t test.