Table 2.

Inflammatory cell density in relation to COX-2 expression in prostate cancer tissue of various Gleason scores

Gleason scoreCOX-2 expressionT-lymphocyte density*
Macrophage density*
Mean ± SDPMean ± SDP
≤7Negative5.88 ± 3.452.22 ± 1.35§
Positive10.94 ± 7.730.0013.89 ± 2.25<0.0001
>7Negative4.98 ± 2.493.86 ± 2.93§
Positive7.45 ± 3.580.0284.83 ± 3.370.533
  • COX-2 expression: negative means COX-2 immunohistochemical score (HPF × 400) is less than 1. Positive means COX-2 immunohistochemical score is 1 or >1.

  • * T-lymphocyte and macrophage densities mean the counting of CD3- or CD68-marked inflammatory cells under the HPF × 400.

  • P = 0.585.

  • § P = 0.042.

  • P = 0.102.

  • P = 0.696.