Gleason score | COX-2 expression^{†} | T-lymphocyte density* | Macrophage density* | ||||
---|---|---|---|---|---|---|---|

Mean ± SD | P | Mean ± SD | P | ||||

≤7 | Negative | 5.88 ± 3.45^{‡} | 2.22 ± 1.35^{§} | ||||

Positive | 10.94 ± 7.73^{∥} | 0.001 | 3.89 ± 2.25^{¶} | <0.0001 | |||

>7 | Negative | 4.98 ± 2.49^{‡} | 3.86 ± 2.93^{§} | ||||

Positive | 7.45 ± 3.58^{∥} | 0.028 | 4.83 ± 3.37^{¶} | 0.533 |

↵† COX-2 expression: negative means COX-2 immunohistochemical score (HPF × 400) is less than 1. Positive means COX-2 immunohistochemical score is 1 or >1.

↵* T-lymphocyte and macrophage densities mean the counting of CD3- or CD68-marked inflammatory cells under the HPF × 400.

↵‡

*P*= 0.585.↵§

*P*= 0.042.↵∥

*P*= 0.102.↵¶

*P*= 0.696.