Table 2.

Expression of mGluR4 according to clinicopathologic features

Expression of mGluR4
Clinicopathologic findings+++P
Size (mean, cm)5.565.494.980.675
Location
    Proximal (n = 53)232910.465
    Distal (n = 188)879011
Histology
    Well (n = 33)82320.028
    Moderate/poor* (n = 208)1029610
Lymphatic invasion
    Absent (n = 169)7485100.467
    Present (n = 72)36342
Venous invasion
    Absent (n = 230)104114120.667
    Present (n = 11)650
Depth of invasion
    T1/T2 (n = 36)201600.199
    T3/T4 (n = 205)9010312
Lymph node metastasis
    Absent (n = 129)556950.336
    Present (n = 112)55507
Distant metastasis
    Absent (n = 191)909290.655
    Present (n = 50)20273
Stage
    Stage I + II (n = 117)526140.464
    Stage III + IV (n = 124)58588
Recurrence
    Absent (n = 154)737740.034
    Present (n = 53)21266
Microsatellite instability
    Absent (n = 209)9510590.975
    Present (n = 23)11111
p53 expression§
    Absent (n = 94)434740.874
    Present (n = 142)66688
Adjuvant therapy
    Not done (n = 180)8189100.764
    Done (n = 61)29302
    Disease-free survival (mean duration, mo)5255300.018
  • * Including 16 cases of mucinous type.

  • Recurrence in 218 cases underwent curative resection; no staining results in 11 cases.

  • No microsatellite instability analysis in nine cases.

  • § No staining results in five cases.