Table 1.

FK866 induced mammary carcinoma growth delay with treatment schedule I (25 mg/kg × 8) and schedule II (40 mg/kg × 4)

Treatment groupsInitial tumor volume before treatment, mm3 (mean ± SE)Time to reach 2× initial tumor volume, d (mean ± SE)
Control (n = 10)126.0 ± 7.82.4 ± 0.2
FK866 (25 mg/kg × 8), n = 7135.7 ± 10.54.3 ± 0.3*
FK866 (40 mg/kg × 4), n = 17127.3 ± 8.05.2 ± 0.5
  • * P < 0.002.

  • P < 0.0002.