Table 2.

Adverse events experienced by more than one subject in all treatment groups

Body system eventGrade level*Dose (μg/kg)
310301002003006001,000Total
n3436333328
No. subjects with any event3336333327
Cardiac disorders
    Sinus bradycardia33
21
111
Gastrointestinal disorders
    Nausea311
2112
113111
General disorders
    Chills321
21111111
111132312
    Pyrexia320
2121
122331311
Musculoskeletal and connective tissue disorders
    Arthralgia315
211
111
Nervous system disorders
    Headache310
21
11211121
Skin and s.c. tissue disorders
    Rash35
211
112
Vascular disorders
    Hypotension3118
21
111111
    Hypertension32
2
12
  • * There were no grade 4 adverse events reported.

  • Includes preferred terms of rash and rash papular.