Table 1.

Genes in the STAT pathway either up-regulated or down-regulated by the treatment with CDDO-Imidazolide

GeneFold induction
CEBPB2.1
IL22RA10.5
IL2RG0.6
ISGF3G5.7
JUNB2.2
NMI0.2
PIM13.2
SMAD12.4
SMAD73.0
SOCS15.9
  • NOTE: A549 cells were treated with 1 ╬╝mol/L CDDO-Imidazolide for 4 hours, and total RNA was isolated and analyzed using a human JAK/STAT Oligo GEArray blot. The expression of the listed genes changed following treatment with CDDO-Imidazolide compared with untreated control cells.