Table 2.

Quantitation of GCC in apical membranes of normal intestinal mucosa, adenomas, and colorectal tumors by immunohistochemistry

Intensity of apical staining
1+2+3+Mean
Small intestine (n = 10)*0732.3
Normal colon (n = 46)143111.5
Adenoma (n = 26)08182.7
Colon carcinoma (n = 24)04202.8
  • * Includes sections from duodenum and ileum.

  • P < 0.001, compared with normal colon by the exact Kruskal-Wallis test.

  • Normal colonic tissue adjacent to adenoma or adenocarcinoma.