Table 2.

Adverse events without regard for causality

DescriptionGrade (n)
Total
1234
Rectal bleeding11
Dyspepsia (heartburn)516
Diarrhea516
Nausea224
Vomiting112
Anorexia246
Abdominal pain33
Anemia2417
Neutropenia2114
Thrombocytopenia2259
Skin rash47213
Urticaria11
Serum creatinine elevation213
Elevated alanine aminotransferase1214
Hypertension1113
Edema437
Headache213
Upper respiratory tract infection314
Pneumonia11
Cough516
Dyspnea2215
Fatigue or weakness125623
Weight loss224
Deep vein thromboses22
Pulmonary embolism11
Supraventricular tachycardia22