Table 4.

Model-based estimates of mean (SE) Photofrin levels in tumors from different cohorts (and subcohort for gastrointestinal)

Cohort (n)Photofrin, mean (SE)P
Gastrointestinal
    Colon (n = 14)2.45 (0.33)<0.0001
    Gastric (n = 2)3.32 (0.77)<0.0001
    Pseudomyxoma (n = 3)0.93 (0.70)0.190
    Appendiceal (n = 3)2.09 (0.80)0.013
    Small bowel (n = 1)5.31 (1.12)<0.0001
Ovarian (n = 10)3.72 (0.40)<0.0001
Sarcoma (n = 16)2.13 (0.33)<0.0001
  • NOTE: For each cohort, P values are for the hypothesis test of detectable (nonzero) mean levels of Photofrin.