Table 5.

The TTNR of Photofrin uptake as a function of normal tissue site

Normal tissueTTNR median (range, n)
Appendix0.14 (NA, n = 1)
Fat2.09 (0.4-5.0, n = 9)
Gall bladder0.74 (0.5-1.0, n = 2)
Large intestine mucosa0.51 (0.2-0.8, n = 2)
Large intestine with mucosa*1.13 (0.2-2.3, n = 9)
Large intestine without mucosa*2.08 (0.8-4.5, n = 3)
Liver0.05 (0.0-0.1, n = 2)
Mesentery1.84 (NA, n = 1)
Muscle6.17 (NA, n = 1)
Omental bursa2.30 (0.3-9.3, n = 13)
Other1.35 (1.0-2.3, n = 5)
Pancreas0.63 (NA, n = 1)
Peritoneum1.07 (NA, n = 1)
Small intestine mucosa0.87 (0.3-1.5, n = 3)
Small intestine with mucosa*0.83 (0.2-3.8, n = 18)
Small intestine without mucosa*2.09 (1.3-3.6, n = 4)
Skin1.86 (0.6-10.3, n = 3)
Spleen0.10 (0.0-0.2, n = 2)
Stomach2.59 (NA, n = 1)
  • NOTE: TTNRs were calculated for individual normal tissues within a patient based on the average Photofrin concentration in tumor and normal samples of the same patient. Listed are median values among all patients with a TTNR available for the indicated normal tissue; an individual patient may contribute to more than one normal tissue site. Parentheses contain the interpatient range in TTNRs and the number of patients (n) contributing data to each site.

  • * Previously reported in ref. (4).