Table 2.

Dose levels of bivatuzumab mertansine administered

Dose (mg/m2/wk)No. patientsBSA (m2)*Total no. doses administeredCumulative dose (mg)
2011.93114
4011.93228
6011.83324
8011.83432
10012.1/2.03 + 3630 + 600
12011.63576
14011.72476
  • * BSA, body surface area according to Du Bois and Du Bois (25).

  • Weight was decreased at start second course; body surface area was recalculated.