Table 1.

Shh and Gli1 protein expressions in 43 human esophageal cancers resistant to chemoradiation

Total (43)Gli1 expression*
NegativeLowModerateStrong
Shh (+)382 (4.6)9 (21.0)15 (34.8)12 (27.9)
Shh (−)55 (11.7)0 (0.0)0 (0.0)0 (0.0)
  • * Gli1 nuclear staining in tumor cells is defined as negative (0% stained cells), low (1% to <30% stained cells), moderate (≥30 to <60% stained cells), and strong (≥60% stained cells).

  • Shh cytoplasmic immunolocalization in tumor cells.