Table 1.

Patient disposition

CharacteristicN = 23
Male, n (age range), median age, y11 (39-84), 63
Female, n (age range), median age, y12 (41-74), 62
Cancer diagnosis
    Lung5
    Breast4
    Colon3
    Mesothelioma3
    Prostate2
    Bladder1
    Ovarian1
    Gastric1
    Osteogenic sarcoma1
    Testicular germ cell1
    Renal cell1
Prior systemic anticancer therapies, n
    10
    23
    ≥320
Prior radiation therapies, n
    13
    24
    ≥34
Discontinued, n9
    Clinical adverse experience7
    Progressive disease1
    Withdrew consent1
Completed trial, n14*
  • * Patients who completed Day 28 dosing and pharmacokinetics.