Table 2.

Summary of RTK biochemical data and relative quantification by quantitative real-time PCR for the corresponding mRNAs with respect to a normal tissue pool

CaseProtein
mRNA
PDGFRB
PDGFRA
KIT
PDGFRB (2−ΔΔCt)PDGFRA (2−ΔΔCt)c-Kit (2−ΔΔCt)
ExprPhosphIHCExprPhosphIHCExprPhosphIHC
1+P8 × 10−12 × 10−12 × 10−1
2+P++5 × 10−12 × 10−12 × 10−2
3++2.54 × 10−13
4+P+P+P6 × 10−16 × 10−23 × 10−1
5+P+P+P6 × 10−13 × 10−12 × 10−1
6+PNENENE
7++10.52NE
8+++NE1.23 × 10−1
9++P55 × 10−14
10NENENE
11++15.61.88 × 10−1
12NENENE
13+P++4 × 10−12 × 10−16 × 10−1
146 × 10−11 × 10−14 × 10−1
15+P++NENENE
16++311
17++P++P++P1.41.22
18+P++P++PNE31.6
19++P++P++P1.41.22 × 10−1
20+P++P++P3 × 10−11 × 10−11 × 10−1
21+P++P++P2.5 × 10−11 × 10−18 × 10−2
22++P++P++P11 × 10−15 × 10−2
23++P++P++P1.33 × 10−12 × 10−1
24+P++P++P3 × 10−11 × 10−24 × 10−2
25+P++P++P5 × 10−14 × 10−13 × 10−1
26+P++P++P2.5 × 10−13 × 10−11 × 10−1
27NE21.2
28NENENE
29NENENE
30NENENE
31NENENE
Median value2.340.70.7
  • NOTE: The values reported on mRNAs are expressed as fold expression compared with normal tissue pool.

    Abbreviations: Expr, receptor expression; Phosph, receptor phosphorylation and thus activation; IHC, immunohistochemical analysis; NE, not evaluable.