Table 3.

Summary of the sequencing data and reverse transcription-PCR on the cognate ligands

CasePDGFRBPDGFBPDGFRAPDGFAc-KitSCF
1wt+S478P, G2203A, C2866T+wtL/S
2wt+wt+C2394TL/S
3wt+C2866T+M541L, G2586CL
4wt+wt+M541LL/S
5wt+wt+M541LL/S
6A2957G+wt+M541LL/S
7wt+wt+M541LL
8G2840A, A2957G+wt+wtL/S
9A2957G+wt+M541LL/S
10A2957G+wt+wtL/S
11G2210A, A2957G+wt+wtL/S
12wt+wt+M541LL/S
13wt+wt+A1638GL/S
14wt+wt+wtL/S
15C2441A, A2957G+S478P, G2203A, C2866T+A1638GL/S
16wt+wt+wtL/S
17A2957G+wt+wtL/S
18wt+wt+wtL/S
19A2957G+S478P, G2203A, C2866T+wtL/S
20G2210A, A2957G+wt+wtL/S
21A2957G+wt+wtL/S
22wt+S478P, G2203A, C2866T+M541LL/S
23A2957G+wt+M541LL/S
24A2957G+wt+wtL/S
25wt+wt+M541L, G2586CL/S
26A2957G+wt+wtL/S
27wt+wt+C2394TL/S
28wt+wt+C2394TL/S
29wt+wt+wt
30NE+NE+M541L
31NE+G2203A, C2866T+wt
  • Abbreviations: wt, wild-type; L, soluble SCF; S, membrane-bound SCF.