Table 2.

Serum mesothelin in relationship to mesothelin expression by tumors

Tumor typeTumor mesothelin expression by immunohistochemistry*nElevated serum mesothelin (%)
Mesothelioma+4334 (80%)
136 (46%)
Ovarian cancer+1612 (75%)
52 (40%)
  • * Tumors were considered mesothelin positive (+) if ≥30% of tumor cells had cell surface expression of mesothelin and negative (−) if <30% of tumor cells expressed mesothelin.

  • Serum mesothelin levels were considered elevated if ≥9 ng/mL.