Table 4.

Responding population of dogs treated with ABT-526

Breed/study no.Tumor histologyTNM stageResponseResponse duration (d)
Labrador retrieverNasal adenocarcinomaT3bN0M0CR165
Corgi mixCutaneous lymphomaCutaneousPR185
Labrador retriever mixNasal carcinoma (SCC)T3bN1M0PR>100
Cocker spanielNHLIIIbPR60
Golden retrieverSoft tissue sarcomaT(sx)N1M1PR>270
Doberman mixNHLIIIaPR90
Miniature poodleCutaneous lymphomaCutaneousPR150
English cocker spanielGI adenocarcinoma (apocrine gland)T(sx)N2M0CR>195
Labrador retriever mixNHLIIIaPR>1,310
Rottweiler mixOral carcinoma (SCC)T2N0M0PR>1,090
Sheltie mixMammary adenocarcinomaT(sx)N1M0SD>900
Golden retrieverNHLIVaSD90
Cairn terrierCutaneous basal cell carcinomaT(sx)N1M0SD90
Shetland sheepdog mixMammary adenocarcinomaT(sx)N2M0SD90
Cocker spanielNHLIIIaSD60
Border collieThyroid adenocarcinomaT2bN0M0SD180
Golden retrieverAbdominal carcinoma GIT2N1M0SD150
Labrador retriever mixBasal cell carcinomaT2bN0M0SD90
AiredaleTracheal chondrosarcomaT(sx)N0M1SD180
  • Abbreviations: SCC, squamous cell carcinoma; NHL, non–Hodgkin's lymphoma; GI, gastrointestinal tract; TNM, tumor-node-metastasis; CR, complete response; PR, progressive disease; SD, stable disease.