Table 2.

Demographic and lung cancer data by sex and tumor PTHrP expression

All patients
Females
Males
PTHrP positivePTHrP negativePTHrP positivePTHrP negativePTHrP positivePTHrP negative
Total no.134 (100)273 (100)46 (100)78 (100)88 (100)194 (100)
Stage
    I73 (53)153 (56)27 (59)48 (61)46 (52)104 (54)
    II14 (10)29 (11)2 (4)3 (4)12 (14)26 (13)
    III30 (22)39 (14)8 (17)9 (12)22 (25)30 (16)
    IV10 (7)13 (5)8 (17)5 (6)2 (2)8 (4)
    Unknown11 (8)39 (14)5 (11)13 (17)6 (7)26 (13)
Histology
    Adenocarcinoma56 (42)136 (50)17 (37)*46 (59)*39 (44)89 (46)
    Squamous65 (47)114 (41)24 (52)*27 (35)*41 (47)87 (45)
    Large cell12 (8)22 (8)5 (11)*5 (6)*7 (8)17 (8)
    Unknown1 (1)1 (1)0 (0)*0 (0)*1 (1)1 (1)
Smoking
    Yes88 (66)193 (71)25 (91)52 (67)63 (72)141 (72)
    No4 (4)18 (7)3 (4)11 (14)3 (3)7 (4)
    Unknown18 (30)61 (22)18 (5)15 (19)22 (25)46 (24)
    Smoker pack-years50 (6, 160)60 (2, 200)50 (6, 100)48 (2, 175)52 (15, 160)60 (3, 200)
Hospital
    VASDHS28 (21)76 (28)0 (0)0 (0)28 (32)76 (39)
    UCSD72 (54)149 (55)30 (65)67 (86)42 (48)82 (42)
    Cytomyx34 (25)48 (17)16 (35)1 (14)18 (20)36 (19)
Age (y)69 (43, 82)64 (19, 89)69 (49, 80)65 (19, 89)69 (43, 82)64 (25, 87)
  • NOTE: Data are number (% column total) or median (range).

  • * P = 0.054, Fisher's exact test, excluding the unknown category.

  • P < 0.05, Fisher's exact test, excluding the VASDHS group.

  • P < 0.05, PTHrP-positive versus PTHrP-negative patients.