Table 1.

Histochemical analysis from tumor specimen in Figure 2

Tumor volume (cm3)Proliferative activity (Ki67)Vessels (CD34)Tumor infiltrating lymphocytes
Control0.5670%30 ± 1+
IMO0.2050%20 ± 2++
Cetuximab0.1710%8 ± 2++
IMO + cetuximab0.133%1massive
  • NOTE: Antibodies are described in Materials and Methods. The massive tumor infiltration of lymphocytes observed in the combination treatment correspond to >20-fold increase compared with untreated control and 12-fold compared with each single agent. Bars, SD.