Table 2.

Relative UGT1A1 expression compared with the control group for each cell line

Colon adenocarcinoma cell linesControl for 5-Aza-dC (PBS)Control for TSA (DMSO)5-Aza-dC (fold increased)TSA (fold increased)5-Aza-dC + TSA (fold increased)
HCT-1161119 (19)1 (1)128(128)
COLO-320DM1115 (15)1 (1)75 (75)
HCT-153092442,132 (7)293 (1)4,075 (13)
  • NOTE: Cells were treated as described in Materials and Methods with 5-Aza-dC alone (5 ╬╝mol/L) or in combination with trichostatin A (300 nmol/L).