Table 2.

In vitro stimulation of CD4 T cells with autologous CHP/ESO-loaded DCs

HLA-DRB1Number of IFNγ ELISPOTs
v.v. ESOv.v. WT
HD1*1101/*1502145 ± 11.342 ± 13.4
HD2*1405/*1502114 ± 2.131 ± 10.6
HD4*0901/*1401105 ± 8.534 ± 11.7
  • NOTE: Production of IFNγ ELISPOTs by CD4 T cells (2 × 104) stimulated twice (HD1) or thrice (HD2 and HD4) with autologous CHP/ESO-loaded DCs against autologous EBV-B cells (2 × 104) infected with v.v. ESO or v.v. WT. Assays were done in duplicate. Values are the means ± SD. The data are representative data from one of three experiments.