Table 2.

Reproducibility and validity of the bead-based assays

Reproducibility
Validity
CA125 RDI assay
CA125 FIII assay
HE4 assay
CA125 RDI/RIA
CA125 FIII/RIA
nrnrnrnrr
Overall1970.991950.951940.952040.950.91
Cases641.00640.93620.94660.930.88
Non-cases (total)1330.941310.891320.891380.850.80
    Surgical690.98680.97690.90720.910.81
    Screening640.83630.64630.86660.640.73
  • NOTE: Reproducibility of case and control measurements for the CA125 RDI, CA125 FIII, and HE4 bead-based assays was assessed by Pearson correlation (r) between two replicate experiments, calculated on the log scale. Validity of the CA125 RDI and FIII bead-based assays was assessed by Pearson correlations with the research standard CA125II RIA (CA125 RDI/RIA and CA125 FIII/RIA, respectively), calculated on the log scale.