Table 2.

Median survival times of C4-2 tumor-bearing animals treated with PSMA ADC

Test articleDose (mg/kg)ScheduleMedian survival (d)
Study 1
    VehicleNAq4d × 332
    PSMA ADC258*
    PSMA ADC1095*
Study 2
    VehicleNAq4d × 629
    PSMA mAb631
    Control ADC631
    PSMA ADC349*
    PSMA ADC6148*
  • Abbreviation: NA, not available.

  • * Significant (P < 0.005) improvement in survival over vehicle control group in a two-sided log-rank analysis.