Table 3.

Univariate and multivariate analyses of clinicopathologic variables and class III β-tubulin status as prognostic factors for overall survival in advanced ovarian cancer patients

VariableUnivariate
Multivariate*
RR1χ2PRR2χ2P
Age (y)
    <651010
    >652.46.00.0142.33.00.08
Stage
    III10
    IV1.10.10.8
Ascites
    No10
    Yes1.40.60.3
Extent of residual tumor (cm)
    <0.51010
    >0.51.82.90.071.98.70.003
Response to treatment
    No10
    Yes1.81.40.2
β III tubulin expression
    Low1010
    High3.311.10.00093.14.60.032
  • NOTE: RR1, unadjusted relative risk; RR2, relative risk after adjusting for all the factors listed; 10, reference category; χ2 of the model = 14.3; P = 0.0008.

  • * Only variables with P < 0.10 in the univariate analysis were included in the multivariate model.

  • Obtained at interval debulking surgery.