Table 2.

AUCs for different comparisons

	*Any pleural disease vs AE AUC (95% CI)**	Malignant vs benign pleural disease^† AUC (95% CI)
Serum osteopontin	0.735 (0.677-0.793)	0.710 (0.647-0.773)
Plasma osteopontin	—	0.729 (0.631-0.827)^‡
Pleural osteopontin	—	0.478 (0.332-0.624)^‡
Serum mesothelin	0.741 (0.684-0.799)	0.784 (0.727-0.842)
Pleural mesothelin	—	0.646 (0.542-0.749)^‡

↵* Pleural disease includes MPM, Mets, and BPLAE.
↵† Malignant pleural diseases include MPM and Mets, and benign pleural diseases include BPLAE and AE.
↵‡ These comparisons include only patients with BPLAE in the benign pleural disease group.