Table 1.

HPLC-MS analysis of species related to silibinin in plasma from humans who had received silibinin (1,440 mg) daily for 7 days as silipide capsules

m/z [M-H+]InferenceRetention time (min)
481Silibinin20.8; 21.4
657Silibinin glucuronide12.6; 15.6; 16.4; 17.8
833Silibinin diglucuronide9.2; 10.8
561Silibinin sulfate17; 17.8; 18.8