Table 1.

In vitro kinase assay of AZD2171 against FGFR2

Cell lineKmKi (μmol/L)
KATO-III8.3 ± 3.30.067 ± 0.017
OCUM2M7.1 ± 1.40.072 ± 0.022
OKAJIMA11.0 ± 5.00.049 ± 0.041