Table 1.

Patient, tumor, and treatment characteristics and cause-specific survival

No. patients (%)P
Age, median (range)56, 39-840.93*
Sex
    Male22 (73)
    Female8 (27)
Smoking history before diagnosis
    Yes20 (67)0.05
    No10 (33)
Smoked during treatment
    Yes2 (7)0.43
    No28 (93)
Smoked after treatment
    Yes4 (13)0.43-0.49
    No26 (87)
Site of primary tumor
    Oropharynx30 (100)
        Tonsil17 (57)
        Base of tongue11 (37)
        Other2 (6)
Stage
    III4 (13)0.99
    IV26 (87)
T classification§
    12 (7)0.46
    25 (17)
    37 (23)
    416 (53)
N classification
    01 (3)0.81
    14 (13)
    2a5 (17)
    2b5 (17)
    2c10 (33)
    35 (17)
Initial treatment modality
    Radiation/neoadjuvant chemotherapy1 (3)
    Radiation/concurrent chemotherapy29 (97)
    Radiation/adjuvant chemotherapy3 (10)
  • * Cox proportional hazards model relating age to cause-specific survival.

  • Log-rank test relating variable to cause-specific survival.

  • Range represents P values from relationship between smoking at the 3-, 6-, 9-, or 12-mo follow-ups with cause-specific survival.

  • § T classification dichotomized to ≥ or < stage IV, log-rank test.

  • N classification dichotomized to ≥ or < N2, log-rank test.

  • Three patients received both concurrent and adjuvant chemotherapy/X-ray therapy.