Table 1.

Univariate analysis of the overall survival of gastric cancer patients using Kaplan-Meier survival analysis

VariablesNo. of patientsOverall survival (%)
P
1 y3 y
Sex
    Male7484.9669.70
    Female4082.5055.000.176
Age
    <605485.1968.22
    ≥606083.0761.030.251
Tumor stage
    I–II5298.0498.04
    III3683.3352.78
    IV2657.69<0.0001*
Tumor size (diameter, cm)
    <5.04989.6283.32
    ≥5.06580.0050.770.0004*
Gross type
    Advanced gastric cancer8278.0551.22
    Early gastric cancer32100100<0.0001*
Grade
    Sig-I4297.6285.16
    II-III7276.3952.780.0003*
Histologic type
    Intestinal6784.8761.83
    Diffuse4582.2266.67
    Mix21001000.578
Chemotherapy
    No6582.8371.83
    Yes4985.7155.100.123
SMAD4 (cytoplasmic staining)
    <13680.5652.78
    ≥17885.7469.980.047*
SMAD4 (nuclear staining)
    <14673.9152.17
    ≥16891.0973.000.015*
SMAD4 LOH
    −5075.5450.48
    +2080.0060.000.910
SMAD4 methylation
    −6979.7460.66
    +475.000.791
  • * Statistically significant.