Table 4.

The response to 5-FU plus oxaliplatin treatment in metastatic colorectal cancer patients with different EGFR codon 497 status

ResponseG/G (wild-type), n (%)G/A or A/A, n (%)P*
All patients enrolled38 (100)71 (100)
    OR (CR + PR)13 (34.2)44 (62.0)0.02
    CR2 (5.3)6 (8.5)
    PR11 (28.9)38 (53.5)
    SD18 (47.4)19 (26.8)
    PD7 (18.4)8 (11.3)
  • Abbreviations: OR, overall response; CR, complete remission; PR, partial remission; SD, stable disease; PD, progressive disease.

  • * Comparison of overall response rate between patients with different EGFR codon 497 polymorphisms.